RNA silencing is a complex, highly-conserved, transcriptional and post-transcriptional mechanism that tunes gene expression. RNA silencing is mediated by molecules known as small RNAs (sRNAs). Well-known examples of sRNAs include short-interfering RNA (siRNA), microRNAs (miRNAs), trans-acting short-interfering RNA (tasi-RNA) and Piwi-interacting RNA (piRNA). It was originally studied as a defence mechanism against pathogens in plants and later studied extensively due to its ability to regulate cancer-related genes. The UEA sRNA Workbench is a collection of software tools specifically designed to identify and analyse features in small RNA data related to this topic.

You can now find the UEA small RNA Workbench on the Eagle Genomics The Elements of Bioinformatics A complete list of tools that Eagle integrates into any bioinformatics pipeline. Learn more

If you use the UEA sRNA Workbench in your research please visit our How To Cite Us pages

Please see the publications category for further research papers that have utilised the UEA sRNA Workbench or toolkit.Thank you.

Funding to create The UEA sRNA workbench was provided by the Biotechnology and Biological Sciences Research Council (grant BB/100016X/1).

Licence for the software can be found here.

A suite of tools for analysing micro RNA and other small RNA data from High-Throughput Sequencing devices